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Absolute Structure Determination and Crystal Identification
The Gold Standard for Crystal Identification

Confirming the absolute configuration and identifying crystal forms using high-resolution structural data and molecular architecture defined by advanced techniques like SCXRD and MicroED.

High Success Rate in Structure Determination

While industry success rates for single-crystal growth are typically limited, our specialized methodologies and crystallization strategies enable reliable results for complex drug molecules.

>90%
Tiered Analytical Approach
Advanced Instrumentation
SCXRD

Utilizing two advanced diffractometers to support structure determination for the majority of crystalline samples.

Synchrotron XRD

Access to the National Synchrotron Light Source II for high-resolution data from challenging samples as small as 1–20 µm.

MicroED

Applied to micro- and nanocrystals (typically <1 µm) when conventional X-ray methods are not feasible.

Single Crystal X-ray Diffraction (SCXRD)
  • Rapid determination: Data collection and analysis can be completed within minutes for suitable samples.
  • High sensitivity: Capable of resolving structures from samples as small as ~10 µm.
  • Proven reliability: Extensive experience across a wide range of pharmaceutical compounds.
SCXRD Instrument
MicroED Instrument
Microcrystal Electron Diffraction (MicroED)
  • Nanocrystalline Suitability: Enables structure determination for samples <200 nm.
  • Resolution: High signal-to-noise ratio and spatial resolution from extremely small crystals.
  • Simultaneous Capability: Combines structural analysis with real-time imaging.

Achieve Your Success with Our Expertise

Have a question or need support with your project? Please complete the form, and our team will get back to you shortly.




Our capabilities span three specialized platforms:

  • Small Molecule

  • Crystal Bio Solutions

  • Crystal NAX


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Related Resources
Small Molecule Crystal Bio Solutions
Biologics Characterization and CMC Analytics Bioanalytical and Biomarker Services Quantitative Clinical Pharmacology (QCP)
Crystal NAX
DNA Synthesis RNA Synthesis LNP Formulation Services Analytical & Characterization Services Early-Phase Manufacturing Catalogue Products
Contact Us
bd_global@crystalpharmatech.com (925) 558-5040
U.S
NJ Sites: Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey, USA 08512

2005 Eastpark Blvd, Cranbury, New Jersey, USA 08512

CA Site: 7133 Koll Center Parkway, Suite 200, Pleasanton, California, USA 94566
Canada
6800 Kitimat Rd, Unit 1, Mississauga, Ontario, Canada L5N 5M1
China
No. 288, Jiangyun Road, Suzhou Industrial Park, Suzhou, China 215123

Floor 1, Bldg. 3, 68 Chunpu Road, Suzhou Industrial Park, Suzhou, China 215123
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NJ Sites: Suite 500-B, 3000 Eastpark Blvd, Cranbury, New Jersey, USA 08512

2005 Eastpark Blvd, Cranbury, New Jersey, USA 08512

CA Site: 7133 Koll Center Parkway, Suite 200, Pleasanton, California, USA 94566
bd_global@crystalpharmatech.com (925) 558-5040